Interior Minister Ali Yerlikaya said 357 suspects were apprehended across 21 provinces in coordinated raids on Tuesday morning.
It comes just a day after three police officers and six alleged militants were killed during an eight hour siege in the northwestern town of Yalova. Another eight police officers and a security force member were injured.
Less than a week ago, authorities arrested another 115 suspects who prosecutors said had been planning attacks targeting non-Muslims during Christmas and New Year's.
