As of Friday night, 1,600 flights across the US had been cancelled and 7,400 had been delayed, according to flight tracking website FlightAware.BBC reported.
The most affected airports are John F Kennedy International, Newark Liberty, and LaGuardia, which all serve the New York area. Boston, Chicago, and Toronto, Canada, are also impacted.
The National Weather Service issued a winter storm warning from 16:00 local time (21:00 GMT) on Friday until 13:00 on Saturday, with as much as 9in (23cm) of snow expected in New York and southern Connecticut.