At least three people have died after a UPS cargo plane crashes during takeoff at Louisville International Airport in Kentucky

A number of nearby businesses have been hit, with officials saying several people are still missing and they expect the death toll to grow

The aircraft was carrying a large amount of fuel when it burst into flames, the local mayor says, with footage from the scene showing fires are still burning

In a statement, UPS says three crew were on board - all are still unaccounted for

UPS Flight 2976, which was bound for Hawaii, crashed at around 17:15 local time, the US Federal Aviation Administration says